Stub1 chip

Author: znjl

August undefined, 2024

WebNov 4, 2024 · Structure of the STUB1 TPR domain in complex with H204, an all-D Helicon Polypeptide WarningYou are using a web browser that we do not support. Our website will not work properly. Please update to a newer version or download a new web browser, such as Chrome or Firefox. Contact us Toggle navigationRCSB PDB Deposit Prepare Data … WebSTIP1 Homology and U-box Containing Protein 1 (STUB1), also known as Carboxyl Terminus of Hsp70-interacting Protein (CHIP), is a cytoplasmic protein that functions as a U-box Ubiquitin ligase (E3) (1). It is highly expressed in striated muscle and brain and has been observed at lower levels in other organs including the pancreas, lung, liver ...

STUB1 STIP1 homology and U-box containing protein 1 [ (human)]

WebSTUB1, also named as CHIP, SDCCAG7, UBOX1 and NY-CO-7, is a E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation. STUB1/CHIP modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90. It mediates transfer of non-canonical short ubiquitin chains to HSPA8 … WebMar 26, 2024 · CHIP/STUB1 Antibody (C-10) is a mouse monoclonal IgG 1 κ, cited in 16 publications, provided at 200 µg/ml. raised against amino acids 73-303 mapping at the C … bonbon chihuahuas for sale

10273 - Gene ResultSTUB1 STIP1 homology and U-box containing prot…

WebAlgoma Steel Inc. (formerly Algoma Steel; Essar Steel Algoma) is an integrated primary steel producer located on the St. Marys River in Sault Ste. Marie, Ontario, Canada.Its products … WebSTUB1/CHIP interacts with Hsp70 to monitor protein folding and direct misfolded proteins for proteasomal degradation. It has been found to also associate with Hsp90 to remove phosphorylated protein tau, a protein that accumulates in the brains of Alzheimers and Down's syndrome patients. WebSTUB1/CHIP Antibody (A301-572A) in WB Detection of human and mouse STUB1/CHIP by western blot (h&m) and immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 µg for WB; 1 mg for IP, 20% of IP loaded), 293T … gnustep graphics

Recombinant Anti-STUB1/CHIP antibody [EPR4448] …

WebSynthetic peptide within Human STUB1/CHIP aa 1-100 (N terminal). The exact sequence is proprietary. Positive control HeLa, MCF-7, 293T and ECV-304 cell lysates; Human skeletal muscle tissue. General notes This … Webnote = "Funding Information: We thank Dr. Ana Maria Cuervo for providing the shRNA against Lamp2a and Atg7 lentiviral vectors, and the NIH-3T3 cells, Dr. Thilo Hagen for the wild-type and proline mutant HIF1A constructs, Dr. Cam Patterson for the wild-type and mutant STUB1 constructs, and Dr. Roland H. Wenger for the Hif1a+/+ and hif1a−/− MEFs. gnu/stubs-x32.h: no such file or directoryWebMar 21, 2024 · STUB1 (STIP1 Homology And U-Box Containing Protein 1) is a Protein Coding gene. Diseases associated with STUB1 include Spinocerebellar Ataxia, Autosomal … bon bon chihuahua

"WebApr 8, 2024 · More interestingly, the E3 ubiquitin ligase STIP1 homology and U-box containing protein 1 (STUB1, also known as CHIP and encoded by STUB1) emerged as … " - Stub1 chip

Stub1 chip

Stub1 STIP1 homology and U-Box containing protein 1 [ (house …

WebOct 15, 2024 · Data indicated that STUB1 deficiency leads both to the intracellular accumulation of protein aggregates and to an increase in the secretion of small … WebThis product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility. - Improved sensitivity and specificity. - Long-term security of supply. - Animal-free production. For more information see here. Our RabMAb ® technology is a patented hybridoma-based technology ...

Did you know?

CHIP enhances HSP70 induction during acute stress and also mediates its turnover during the stress recovery process. Hence CHIP appears to maintain protein homeostasis by controlling chaperone levels during stress and recovery. Mutations in STUB1 cause spinocerebellarataxiatype 16. Interactions. STUB1 … See more STUB1 (STIP1 homology and U-Box containing protein 1) is a human gene that codes for the protein CHIP (C terminus of HSC70-Interacting Protein). See more The CHIP protein encoded by this gene binds to and inhibits the ATPase activity of the chaperone proteins HSC70 and HSP70 and blocks the … See more • Patterson C (Jan 2002). "A new gun in town: the U box is a ubiquitin ligase domain". Science's STKE. 2002 (116): pe4. doi See more STUB1 has been shown to interact with: • C-Raf, • DNAJB1, • HSPA1A, • HSPA4, See more • STUB1 human gene location in the UCSC Genome Browser. • STUB1 human gene details in the UCSC Genome Browser. See more WebSTIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase Synonyms: CHIP, HSPABP2, NY-CO-7, SDCCAG7, UBOX1 Species: Human STUB1 (10273), Mouse Stub1 (56424), Rat Stub1 (287155), Zebrafish... Summary: STUB1, or CHIP, is a ubiquitin ligase/cochaperone that participates in... Related Products:

WebApr 4, 2024 · STUB1 is an intracellular checkpoint for interferon gamma sensing. STUB1-SMYD2 Axis Regulates Drug Resistance in Glioma cells. Regulation of STUB1 expression … WebOct 25, 2005 · Antibodies against STUB1 are found in patients with chronic lymphocytic leukemia (CLL) and in colorectal cancer patients. Catalytic activity S-ubiquitinyl- [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N6-ubiquitinyl- [acceptor protein]-L-lysine. 3 publications

WebDescription: Homo sapiens STIP1 homology and U-box containing protein 1 (STUB1), transcript variant 2, mRNA. (from RefSeq NM_001293197) RefSeq Summary (NM_001293197): This gene encodes a protein containing tetratricopeptide repeat and a U-box that functions as a ubiquitin ligase/cochaperone. The encoded protein binds to and … WebAug 18, 2024 · Stub1 deletion enhances antigen processing and presentation by sensitizing tumour cells to IFNγ. (a – c) Flow cytometry analysis of cell surface MHC-I on parental, control or independent Stub1...

WebSTUB1/CHIP is 303 amino acids (aa) in length with a predicted molecular weight of 34.8 kDa. Human STUB1/CHIP shares 97% aa sequence identity with the mouse ortholog but only 67% sequence identity with the rat …

WebSTUB1/CHIP was also immunoprecipitated by rabbit anti-STUB1/CHIP antibody (Product # A301-573A), which recognizes a downstream epitope. For blotting immunoprecipitated … bon bon children\\u0027s wear tyldesleyWebJul 27, 2024 · The STUB1 gene (STIP1 Homology And U-Box Containing Protein 1) encodes the CHIP protein containing tetratricopeptide repeats and a U-box that functions as a ubiquitin ligase/cochaperone, involved ... gnu technology incWebSee all STUB1/CHIP primary antibodies Description Rabbit monoclonal [EPR4448] to STUB1/CHIP Host species Rabbit Tested applications Suitable for: WB, ICC/IF more details Unsuitable for: Flow Cyt or IHC-P Species … bon bon chicken saladWebAug 12, 2024 · updated on. August 12, 2024. On Highway 17 about an hour north of Sault Ste. Marie, Ontario at Pancake Bay and across from Agawa Crafts & The Canadian Carver, … gnu style designated initializer rangesWebOct 15, 2024 · CHIP/Stub1 interacts with eIF5A and mediates its degradation. Cellular Signalling, Volume 26, Issue 5, 2014, pp. 1098-1104. Show abstract. eIF5A, containing the unusual amino acid hypusine, is a highly conserved protein essential for the proliferation of eukaryotic cells. Previous studies have demonstrated that the activity of eIF5A was ... gnustep application projectWebDescription Rabbit polyclonal to STUB1/CHIP Host species Rabbit Specificity Detects human carboxyl terminus of hsc70-interacting protein (CHIP).Detects a band of approximately 35 kDa representing CHIP from COS-1 cells overexpressing the human gene including a non-specific band at 80kDa . bon bon chicken and pizzaWebSTUB1 encodes for the protein C-terminus of Hsc70 Interacting Protein (CHIP), an E3 ubiquitin ligase. CHIP is known to regulate proteostasis by recruiting chaperones via a N-terminal… Show more bon bon chicken west chester pa